
XERF is a monopolar radiofrequency device that uses two frequencies, 6.78MHz and 2MHz. Rather than stimulating a single depth uniformly, it adjusts the range over which energy is delivered according to skin condition and treatment area, managing loss of firmness and sagging of the facial contour together. Device documentation confirms the two frequencies and the monopolar structure; clinical studies are emerging but still limited in size and follow-up, so the aim should be energy planned around skin thickness and the location of sagging — not a promise of identical lift for everyone.
Contents
What kind of treatment is XERF?
XERF delivers radiofrequency energy into the skin to generate heat in tissue. Monopolar radiofrequency heats skin and subcutaneous tissue and induces change in collagen structure, with remodelling following. Earlier monopolar studies have observed changes in dermal collagen density and arrangement after treatment.
What distinguishes XERF is that it can use two frequencies — 6.78MHz and 2MHz — in one device. Rather than treating the whole face on one setting, thin areas such as around the eyes can be approached differently from thicker areas such as the cheeks and jawline.
How do 6.78MHz and 2MHz differ?
The main difference is how the energy is distributed and at what depth. XERF is designed with three depth settings — shallow, middle and deep. 6.78MHz is used to heat relatively superficial layers, while 2MHz is designed to reach deeper tissue.
In practice, then, it is less about delivering more energy than about judging which depth of heat a given area needs. Whether the main concern is loss of firmness in the skin itself, or sagging of the contour including the cheeks and jawline, changes how energy is allocated.
In a multicentre study of 39 patients treated with dual-frequency monopolar radiofrequency, the improvement rate rose from 84.6% at day 30 to 92.3% at day 90 — collagen regeneration appearing over time.[1]
Which facial concerns does it address?
XERF can be considered where skin firmness has declined or the facial line looks blurrier than before. Because skin thickness and fat volume differ across the face, an area-by-area approach is needed rather than one uniform intensity — the thin, finely controlled periorbital area, laxity of the cheeks and around the mouth, and a jawline that looks less defined than it used to.
A 2026 study of XERF's dual-frequency monopolar radiofrequency applied 6.78MHz and 2MHz to 39 patients with facial laxity according to depth by area, with clinical change observed at day 30 and day 90; it was a short study without a control group, so results cannot be generalised to every patient. A smaller retrospective study of 16 patients also observed changes in the periorbital area, firmness and texture.[2]
What is the difference between 300 and 600 shots?
600 shots do not mean exactly twice the effect or twice the duration of 300. Shot count relates primarily to how wide an area can be treated and how finely.
300 shots can be planned around specific areas of concern such as the periorbital region, cheeks or jawline, while 600 shots allow the whole face to be divided more widely or several areas of firmness and contour to be addressed together. What matters is where your sagging is concentrated and whether whole-face treatment is needed — not simply choosing the programme with more shots.
Read alsoDuration by shot count is covered in “XERF 300 versus 600 shots: why durability differs” (Korean).
What should be checked before treatment?
With XERF, energy settings matched to skin condition and a plan by area matter more than the device name or shot count. Skin thickness, fat volume, facial shape and degree of laxity differ between people, and the periorbital area, cheeks and jawline differ in structure.
Before treatment, confirm which areas you want improved, how shots will be allocated, and at what depth and energy the treatment will run. Redness, warmth, swelling or tenderness can occur temporarily; burns or tissue damage from excessive heat are possible though uncommon, so simply raising intensity is not the answer. Recent studies report mostly transient adverse events, but large long-term data are still limited.
XERF lifting: common myths and facts
| You may think… | In practice |
|---|---|
| "Higher frequency goes deeper." | 6.78MHz handles superficial layers; 2MHz deeper ones. |
| "Hotter is better." | Excess heat risks fat loss and burns, so settings matter. |
| "More shots is always better." | Allocation by area influences the result more than shot count. |
When explaining the two frequencies I put it as “shallow layer for texture and firmness, deep layer for contour”. Knowing which layer your concern sits in makes the shot allocation easy to understand.
XERF is a monopolar radiofrequency device using 6.78MHz and 2MHz, adjusting the range of energy delivery to skin condition and area so that loss of firmness and contour sagging are managed together. 6.78MHz heats superficial layers and 2MHz reaches deeper tissue, which is why the starting point is which layer your concern sits in. In a 39-patient multicentre study the improvement rate rose from 84.6% at day 30 to 92.3% at day 90 — but the evidence base is still short-term and small, so energy should be designed around skin thickness and the location of sagging rather than shot count alone.
🔬 The research behind this article
These are the international journal papers that support the content above. Select a title to open the abstract on PubMed.
- Cureus 2026 — dual-frequency monopolar radiofrequency, 39 patients, multicentreWeiss RA, Wang J, DiBernardo B, Bhatia AC. Clinical Outcomes Following Dual-Frequency Noninvasive Monopolar Radiofrequency Treatment for Facial Laxity and Lower Face Lifting: A Prospective Multicenter Study. Cureus. 2026;18(3):e104546.Key: improvement 84.6% at day 30 → 92.3% at day 90Text [1] · PMID 41930066 · DOI
- Lasers in Medical Science 2026 — retrospective study of XERF, 16 patientsErlich G, Dahan E, Wolf Y. Objective and subjective retrospective evaluation of XERF, a novel single-shot dual-frequency non-invasive monopolar radiofrequency. Lasers Med Sci. 2026;41(1).Key: brow and upper eyelid elevationText [2] · PMID 42611100 · DOI
Frequently asked questions
Is XERF the same as Thermage?
A. Both use monopolar radiofrequency energy. XERF differs in using two frequencies, 6.78MHz and 2MHz.
Can XERF be used around the eyes?
A. The periorbital area has thin skin and needs fine energy control. XERF allows different settings and effectors by area, so it can be considered there, but feasibility and extent are decided after assessing the skin.
Are 600 shots always better than 300?
A. No. 600 shots mainly mean energy can be distributed over a wider area; it does not mean exactly twice the effect or twice the durability.
Do results appear immediately?
A. The heat response begins immediately, but collagen remodelling appears over time; recent studies observed change over one to three months, with individual variation.
Is one session enough?
A. A single number cannot be set for everyone. Studies have evaluated both single and two-session protocols, so the number depends on laxity, skin condition and the change wanted.
📖 References
Select a [number] in the text to jump to the source, and ↩ to return. Only papers whose title, journal and year were verified on PubMed are included.
- Weiss RA, Wang J, DiBernardo B, Bhatia AC. Clinical Outcomes Following Dual-Frequency Noninvasive Monopolar Radiofrequency Treatment for Facial Laxity and Lower Face Lifting: A Prospective Multicenter Study. Cureus. 2026;18(3):e104546. — Cureus 2026 — dual-frequency monopolar radiofrequency, 39 patients, multicentre. ↩
- Erlich G, Dahan E, Wolf Y. Objective and subjective retrospective evaluation of XERF, a novel single-shot dual-frequency non-invasive monopolar radiofrequency. Lasers Med Sci. 2026;41(1). — Lasers in Medical Science 2026 — retrospective study of XERF, 16 patients. ↩
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